The Ultimate American Adventure
Cruise historic waterways and awe-inspiring coastlines
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American Cruise Lines
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7 Night Historic South & Golden Isles
American Independence
Departing from: Jacksonville, FloridaPorts of Call:- Amelia Island, Florida
- Jekyll Island, Georgia
- Savannah, Georgia
- Hilton Head Island, South Carolina
- Beaufort, South Carolina
- Charleston, South Carolina
Sailing Dates:- November 2024
interior fromNot Availableoceanview from$3,965$566pernightbalcony from$4,960$709pernightsuite from$7,205$1,029pernightAll the Cruise Line Offers & More:Riverview from $3,965($566pernight)4.6 rating out of 5 (8 reviews) -
7 Night Lower Mississippi River
American Splendor
Departing from: New Orleans, LouisianaPorts of Call:- Houmas House Plantation, Louisiana
- Baton Rouge, Louisiana
- St. Francisville, Louisiana
- Natchez, Mississippi
- Vicksburg, Mississippi
- River Cruising
- Memphis, Tennessee
Sailing Dates:- November 2024
interior fromNot Availableoceanview from$4,125$589pernightbalcony from$4,735$676pernightsuite from$7,365$1,052pernightAll the Cruise Line Offers & More:Was $5,125 – Save up to 20%Riverview from $4,125($589pernight)4.3 rating out of 5 (3 reviews) -
7 Night Tennessee Rivers
American Splendor
Departing from: Chattanooga, TennesseePorts of Call:- Decatur, Alabama
- Florence, Alabama
- Savannah, Tennessee
- Paducah, Kentucky
- Clarksville, Tennessee
- Nashville, Tennessee
Sailing Dates:- August 2024
- September 2024
- August 2025
interior fromNot Availableoceanview from$4,125$589pernightbalcony from$4,635$662pernightsuite from$7,290$1,041pernightAll the Cruise Line Offers & More:Was $5,635 – Save up to 18%Riverview from $4,125($589pernight)4.3 rating out of 5 (3 reviews) -
7 Night Music Cities
American Splendor
Departing from: Nashville, TennesseePorts of Call:- Clarksville, Tennessee
- Dover, Tennessee
- River Cruising
- Paducah, Kentucky
- River Cruising
- Memphis, Tennessee
Sailing Dates:- July 2024
- September 2024
- October 2024
interior fromNot Availableoceanview from$4,125$589pernightbalcony from$4,735$676pernightsuite from$7,365$1,052pernightAll the Cruise Line Offers & More:Was $5,735 – Save up to 17%Riverview from $4,125($589pernight)4.3 rating out of 5 (3 reviews) -
7 Night Puget Sound & San Juan Islands
American Spirit
Departing from: Seattle, WashingtonPorts of Call:- Anacortes, Washington
- Friday Harbor, San Juan Island, Washington
- Cruise San Juan Islands
- Victoria, British Columbia
- Port Townsend, Washington
- Poulsbo, Washington
Sailing Dates:- June 2024
- July 2024
- August 2024
- September 2024
- October 2024
interior fromNot Availableoceanview from$4,730$676pernightbalcony from$5,210$744pernightsuite from$5,030$719pernightAll the Cruise Line Offers & More:Was $6,210 – Save up to 16%Riverview from $4,730($676pernight)4.7 rating out of 5 (11 reviews) -
7 Night Chesapeake Bay
American Independence
Departing from: Baltimore, MarylandPorts of Call:- Yorktown, Virginia
- Crisfield, Maryland
- Cambridge, Maryland
- St. Michaels, Maryland
- Annapolis, Maryland
Sailing Dates:- October 2024
interior fromNot Availableoceanview from$4,425$632pernightbalcony from$5,385$769pernightsuite from$7,900$1,129pernightAll the Cruise Line Offers & More:Was $5,525 – Save up to 20%Riverview from $4,425($632pernight)4.6 rating out of 5 (8 reviews) -
7 Night New England Islands
American Star
Departing from: Providence, Rhode IslandPorts of Call:- New Bedford, Massachusetts
- Nantucket, Massachusetts
- Martha's Vineyard, Massachusetts
- Block Island, Rhode Island
- Newport, Rhode Island
- Bristol, Rhode Island
Sailing Dates:- July 2024
- August 2024
- September 2024
interior fromNot Availableoceanview from$4,540$649pernightbalcony from$5,670$810pernightsuite from$8,220$1,174pernightAll the Cruise Line Offers & More:Riverview from $4,540($649pernight)4.5 rating out of 5 (9 reviews) -
7 Night Maine Coast & Harbors
American Independence
Departing from: Portland, MainePorts of Call:- Bar Harbor, Maine
- Bangor, Maine
- Camden, Maine
- Rockland, Maine
- Boothbay, Maine
- Bath, Maine
Sailing Dates:- July 2024
- August 2024
- September 2024
- September 2025
interior fromNot Availableoceanview from$4,540$649pernightbalcony from$5,670$810pernightsuite from$8,220$1,174pernightAll the Cruise Line Offers & More:Riverview from $4,540($649pernight)4.6 rating out of 5 (8 reviews) -
7 Night Puget Sound & San Juan Islands
American Constellation
Departing from: Seattle, WashingtonPorts of Call:- Anacortes, Washington
- Friday Harbor, San Juan Island, Washington
- Cruise San Juan Islands
- Victoria, British Columbia
- Port Townsend, Washington
- Poulsbo, Washington
Sailing Dates:- October 2024
- April 2025
- May 2025
interior fromNot Availableoceanview from$4,585$655pernightbalcony from$5,405$772pernightsuite from$6,935$991pernightAll the Cruise Line Offers & More:Was $6,405 – Save up to 16%Riverview from $4,585($655pernight)4.9 rating out of 5 (7 reviews) -
7 Night Music Cities
American Serenade
Departing from: Nashville, TennesseePorts of Call:- Clarksville, Tennessee
- Dover, Tennessee
- River Cruising
- Paducah, Kentucky
- River Cruising
- Memphis, Tennessee
Sailing Dates:- November 2024
interior fromNot Availableoceanview fromNot Availablebalcony from$5,075$725pernightsuite from$7,005$1,001pernightAll the Cruise Line Offers & More:Was $6,075 – Save up to 16%Balcony from $5,075($725pernight) -
7 Night Tennessee Rivers
American Serenade
Departing from: Chattanooga, TennesseePorts of Call:- Decatur, Alabama
- Florence, Alabama
- Savannah, Tennessee
- Paducah, Kentucky
- Clarksville, Tennessee
- Nashville, Tennessee
Sailing Dates:- October 2024
interior fromNot Availableoceanview fromNot Availablebalcony from$5,075$725pernightsuite from$7,005$1,001pernightAll the Cruise Line Offers & More:Was $6,075 – Save up to 16%Balcony from $5,075($725pernight) -
7 Night Historic South & Golden Isles
American Eagle - New Ship!
Departing from: Jacksonville, FloridaPorts of Call:- Amelia Island, Florida
- Jekyll Island, Georgia
- Savannah, Georgia
- Hilton Head Island, South Carolina
- Beaufort, South Carolina
- Charleston, South Carolina
Sailing Dates:- December 2024
interior fromNot Availableoceanview from$6,510$930pernightbalcony from$6,960$994pernightsuite from$7,880$1,126pernightAll the Cruise Line Offers & More:Was $7,960 – Save up to 13%Riverview from $6,510($930pernight)5 rating out of 5 (1 reviews) -
10 Night Northwest Pioneers
American Song
Departing from: Portland, OregonPorts of Call:- Hayden Island, Portland, Oregon
- Astoria, Oregon
- Mount St. Helens, Washington
- Cruise Columbia River, Pacific Northwest, Usa
- Stevenson, Washington
- Hood River, Oregon
- The Dalles, Oregon
- Richland (Tri-Cities), Washington
- Pendleton, Oregon
- Cruise Snake River, Pacific Northwest, Usa
- Clarkston, Washington
Sailing Dates:- September 2024
interior fromNot Availableoceanview fromNot Availablebalcony from$8,180$818pernightsuite from$11,805$1,181pernightAll the Cruise Line Offers & More:Balcony from $8,180($818pernight)5 rating out of 5 (3 reviews) -
14 Night Alaska Inside Passage
American Constellation
Departing from: Seattle, WashingtonPorts of Call:- Anacortes, Washington
- Friday Harbor, San Juan Island, Washington
- Cruise Queen Charlotte Sound, British Columbia
- Cruise Inside Passage, Alaska
- Ketchikan, Alaska
- Wrangell, Alaska
- Petersburg, Alaska
- Cruise Tracy Arm Fjord, Alaska
- Cruise Glacier Bay National Park
- Haines, Alaska
- Skagway, Alaska
- Juneau, Alaska
Sailing Dates:- May 2025
interior fromNot Availableoceanview from$10,385$742pernightbalcony from$12,240$874pernightsuite from$15,570$1,112pernightAll the Cruise Line Offers & More:Was $11,385 – Save up to 9%Riverview from $10,385($742pernight)4.9 rating out of 5 (7 reviews)
See the U.S. Like Never Before Aboard American Cruise Lines
Set sail on the adventure of a lifetime aboard a small cruise ship or riverboat with ample amenities and top-notch service delivered by an all-American crew. A relaxed, casual atmosphere combined with an unparalleled attention to detail will make you feel right at home from the beginning to the end of your journey.
New England itineraries take you to charming seaside towns and islands, cruising the coast from Newport, Rhode Island up to Bar Harbor, Maine. Dive into the area's rich maritime history and taste some of the nation's best seafood along the way.
Across the country to the West Coast, you'll find American Cruise Lines river and ocean sailings to take you through the Pacific Northwest and Alaska. Set out on the very same trail that Lewis and Clark once traversed, see pods of orcas swimming in the Puget Sound, or sample delicious wines in wine country. Each itinerary offers so much to explore.
Sailing the Mississippi is a unique adventure all its own. With river cruises spanning St. Louis, Missouri to St. Paul, Minnesota and Memphis, Tennessee to New Orleans, Louisiana, there's so much to do and see. Visit old plantations and Civil War battlefields, tour the hometown of Mark Twain, and indulge in blues and BBQ.
Experience southern hospitality at its finest aboard Southeast cruises navigating the Intracoastal Waterway and Chesapeake Bay. Historic landmarks and local treasures abound from the great rivers of Florida to the Golden Isles and beyond.
With exceptional cuisine, daily entertainment, and complimentary experiences, traveling aboard an American Cruise Lines world-class ship is a remarkable experience you'll never forget. Book now to begin your next adventure of the United States.